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Replicación viral: Proceso molecular mediante el cual se reproducen los virus.
Tomografía computarizada: (TAC) estudio de imagen con rayos X no invasivo, que permite ver un
órgano más a detalle haciendo “rebanadas” de su imagen.

Referencias

Chu, H., Chan, J. F., Wang, Y., Yuen, T. T., Chai, Y., Hou, Y. et al. (2020). Comparative replication
and immune activation profiles of SARS-CoV-2 and SARS-CoV in human lungs: an ex vivo
study with implications for the pathogenesis of COVID-19. Clinical Infectious Diseases.
doi: 10.1093/cid/ciaa410

Gheblawi, M., Wang, K., Viveiros, A., Nguyen, Q., Zhong, J. C., Turner, A. J, Raizada, M. K., Grant,
M. B. & Oudit, G. Y. (2020). Angiotensin Converting Enzyme 2: SARS-CoV-2 Receptor
and Regulator of the Renin-Angiotensin System. Circulation Research, 126(10). doi:
10.1161/CIRCRESAHA.120.317015

Hamming, I., Timens, W., Bulthuis, M. L., Lely, A. T., Navis, G., & van Goor, H. (2004). Tissue
distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step
in understanding SARS pathogenesis. The Journal of Pathology, 203(2), 631-637. doi:
10.1002/path.1570

Helmy, Y. A., Fawzy, M., Elaswad, A., Sobieh, A., Kenney, S. P., & Shehata, A. A. (2020). The
COVID-19 Pandemic: A Comprehensive Review of Taxonomy, Genetics, Epidemiolo-
gy, Diagnosis, Treatment, and Control. Journal Clinical Medicine, 9(4). doi: 10.3390/
jcm9041225

Hoffmann, M., Kleine-Weber, H., Schroeder, S., Kruger, N., Herrler, T., Erichsen, S., Schier-
gens, T. S., Herrler, G., Wu, N-H., Nitsche, A, Müller, M. A., Drosten, Ch., & Pohlmann,
S. (2020). SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked
by a Clinically Proven Protease Inhibitor. Cell, 181(2), 271-280 e278. doi: 10.1016/j.
cell.2020.02.052

Knudsen, L., & Ochs, M. (2018). The micromechanics of lung alveoli: structure and function of
surfactant and tissue components. Histochem Cell Biol, 150(6), 661-676. doi: 10.1007/
s00418-018-1747-9

¿Cómo nos enferma el
SARS-CoV-2?
Rodríguez, Rodríguez & Romero